MyBioSource.com's MOUSE ANTI RAT CD11b is a Mouse monoclonal antibody. The MOUSE ANTI RAT CD11b Antibody was generated using CD11b, CD11b / CD18, CD11b/CD18, integrin alpha M, Itgam, Ly-40, and MAC1 as the antigen. It reacts with Porcine. This antibody has been shown to work in applications such as: Immunohistochemistry.
Description
Mouse anti Rat CD11b antibody, clone ED8 recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. Mouse anti Rat CD11b antibody, clones ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes